Glimepiride is a sulfonylurea which acts by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin.

Hypoglycemia (low blood glucose level), Taste change, Nausea, Diarrhea, Stomach pain, Headache, Upper respiratory tract infection